من طرف Lara الأربعاء أغسطس 12 2009, 14:18
Betaserk
Roman name
Betaserc
Pharmacokinetics
Rapidly absorbed, slightly associated with plasma proteins. S_max in plasma is a three hour T_1/2, 3-4 p.m. Virtually all news appears in the form of metabolita (2-peridilucsusnoy acid) for 24 h.
Farmakodinamika
Through direct agonistic effect on N_1 receptors receptacles inner ear, as well as indirectly through the impact on N_3 receptors improves the permeability and capillary inner ear, equalizes pressure in endolimpa maze and ulitke increases in the bloodstream baziliarnah arteries. Provides view of the central, normalizes neironalnuu transmission in neuron vestibular nuclei in the trunk brain. Reduces frequency and intensity of dizziness, reduces noise in the ears, improves hearing in the case of lowering it.
Clinical pharmacology
Improvement is usually early in the therapy, sustained therapeutic effect was achieved during the first two weeks of treatment and can grow in the next few months of treatment.
Indications
Vestibular vertigo origin (treatment and prevention); Syndromes characterized golovokrugeniem and headaches, noise in the ears, a progressive reduction hearing, nausea and vomiting; Disease / syndrome Ménière.
Pregnancy and lactation
Not enough data To assess the impact of the drug during pregnancy and breastfeeding.
Contraindications
Гиперчувствительност ь to components of the preparation.
Side-Effects
Digestive disorders. In very rare cases, the emergence of reactions гиперчувствительност и of the skin (rashes, itching, urticaria); Kwinke swelling.
Patient interaction
Cases interaction or incompatibility with other PP unknown.
Precautions
Caution must be exercised in the treatment of patients with gastric ulcers syndrome (incl. history), feohromotsytoma and bronchial asthma (for the period of treatment needed constant monitoring). It has sedative effect and does not affect the ability to drive or work on the machines and mechanisms.
Storage conditions
List B. The temperature 0-25 ° C
Shelf life
5 years
The registration
013149/01-2001
The drug forms
Circle dvoyakovpuklaya tablet white, or almost white with the idea edge and mark. From both sides of the risks are the words : "256" for tablets Betaserk 8 mg; "267" for Betaserk tablets 16 mg; "289" for Betaserk tablets 24 mg, on the other side there is the inscription "S" and the "$ TRWHITE" under